Thanks to a re-infusion of cord blood stem cells, a little girl has recovered from a critical brain injury
Oklahoma Blood Institute asking to support House Bill 2421 to establish a life-saving, public umbilical cord blood bank for our state.
Umbilical Cord Blood Stem Cells: Prime Source for Transplants and Future Regenerative Medicine
Delayed Cord Clamping Protects Newborn Babies from Iron Deficiency, Research Finds
Transplantation of porcine umbilical cord matrix mesenchymal stem cells in a mouse model of Parkinson's disease
Improvement in Cardiac Function following Transplantation of Human Umbilical Cord Matrix-Derived Mesenchymal Cells
The FDA has approved an umbilical cord blood product its first for use in stem cell transplants.
Umbilical cord holds key to heart repair: Study
Recent progress in cell therapy for basal ganglia disorders with emphasis on menstrual blood transplantation in stroke
Umbilical cord blood banking: an update
Broxmeyer HE, Lee MR, Hangoc G, Cooper S, Prasain N, Kim YJ, Mallett C, Ye Z, Witting S, Cornetta K, Cheng L, Yoder MC
C. J. Huang, A. E. Butler, A. Moran, P. N. Rao, J. E. Wagner, B. R. Blazar, R. A. Rizza, J. C. Manivel and P. C. Butler
Company Introduces New Services Designed to Provide Expanded Options to Potentially Extend Future Family Healthcare Protection
An innovative experimental treatment for boosting the effectiveness of stem-cell transplants with umbilical cord blood has a favorable safety profile in long-term animal studies, report scientists from Dana-Farber Cancer Institute, Beth Israel Deaconess Medical Center (BIDMC), and Children's Hospital Boston (CHB).
Company’s Revolutionary Menstrual Stem Cell Technology May Potentially Transform the Stem Cell Industry
A four-year-old girl has become the first patient in Spain to recover from brain cancer after being treated with stem cells from her own umbilical cord blood.
DURHAM, NC – Duke University has received a $10.2 million grant from the Robertson Foundation to create a Translational Cell Therapy Center.
DURHAM, N.C. (Ivanhoe Newswire) -- It's already helping cancer patients and those suffering from blood disorders. Now, doctors are using umbilical cord blood to tackle a whole new set of incurable conditions. From brain damage to diabetes, cord blood is giving kids a better life.
SEATTLE - A major breakthrough in cancer treatment has been by scientists here in Washington
In recent years the science community has been working hard to discover the many uses of stem cells. While some consider the study of stem cells to be controversial, the findings have continued to show endless possibilities. In recent studies researchers have found a link between stem cells and restoring memory capabilities.
In a new research study under way at the Methodist DeBakey Heart & Vascular Center, surgeons are adding a patient’s own stem cells to the heart during cardiac bypass surgery.
Mouse Study May Lead to New Therapies for Parkinson's Disease
Hans Keirstead, a researcher at University of California, Irvine, is set to begin a small human trial of his embryonic stem cell treatment on patients with spinal cord injuries. The treatment is designed for patients within 14 days of suffering spinal cord injuries. In rat trials, paralyzed rats were injected with a stem cell formula. The paralyzed rats were able to walk six weeks later.
After Obama eases restrictions on stem cell research, researchers are almost giddy with enthusiasm about progress
Menstrual Blood Cells Display Stem Cell–Like Phenotypic Markers and Exert Neuroprotection Following Transplantation in Experimental Stroke
Scientists at The University of Nottingham have discovered the gene that enables an extraordinary worm to regenerate its own body parts after amputation — including a whole head and brain.
PALO ALTO, Calif., April 21, 2010 – StemCells, Inc. (NASDAQ: STEM) announced today that it has submitted a protocol to the FDA for initiation of a second clinical trial of its proprietary HuCNS-SC® human neural stem cells in neuronal ceroid lipofuscinosis (NCL), which is also often referred to as Batten disease.
Study in STEM CELLS AND DEVELOPMENT Demonstrates Potential to Reverse Neural Trauma After Stroke
A 10-year-old British boy has become the first child to undergo a windpipe transplant with an organ crafted from his own stem cells.
Neuralstem, Inc. (NYSE Amex: CUR) announced that its stem cell treatment for ALS (Amyotrophic Lateral Sclerosis, or Lou Gehrig's disease), currently in a FDA-approved Phase I clinical trial, was featured on CNN last night with Dr. Sanjay Gupta, in the piece entitled "Stem Cell Medical Breakthrough".
A Columbia scientist has become the first to grow a complex, full-size bone from human adult stem cells.
ROME - The Vatican is pushing for research of adult stem cells as an alternative to the use of embryonic stem cells, which the Catholic Church opposes because it maintains that the destruction of the embryo amounts to the killing of human life.
A couple of Ottawa doctors working with multiple sclerosis patients are reluctant to use "the C word" -- for cure -- but they're drawing hope from their patients, including a Windsor-born man, in long-term remission.
Research study led by Dr. Wise Young of Rutgers will study how stem cell treatments using cord blood could be used to cure spinal cord injuries
Stem cell treatment helps boy with cerebral palsy
Data from an in vitro study presented at the Fourth China Medical Biotech Forum, in Dalian, China indicate that stem cells found in menstrual blood (known as MenSCs) proliferate rapidly and have significant potential to develop into multiple cell types.
Research and development initiatives relating to the use of stem cells from menstrual blood continue to gain momentum, as evidenced by a recent international partnership. U.S.-based stem cell company Cryo-Cell International recently announced an exclusive license agreement with S-Evans Biosciences, Inc. (SEB), a privately-held stem cell and genomics technology company located near Shanghai, China.
The California Institute of Regenerative Medicine (CIRM) has awarded a total of $5.42 million in stem cell grants to four scientists at UCLA's Broad Stem Cell Research Center.
Cryo-Cell International, Inc., a world leader in stem cell innovation, has entered a research and development collaboration agreement with nationally-recognized wound specialist, Dr. Robert J. Snyder and the Snyder Wound Research Institute LLC in Tamarac, FL.
Florida-based Cryo-Cell International, a leader in stem cell cryopreservation, has partnered with Cryopraxis, a Brazil-based company known for its expertise in regenerative technology. The partnership will allow Cryopraxis to conduct clinical studies using Cryo-Cell`s proprietary C`elleSM menstrual stem cell technology (MenSCs) to identify potential future diagnostic and therapeutic uses for endometriosis and stress urinary incontinence in women.
Neuroscientist outlines reasons for changing his position regarding the importance of storing stem cells from cord blood
Proposed legislation promoting awareness for benefits of cord blood storage has bipartisan support
Cincinnati doctors pay to bank stem cells from baby's cord blood.
The Wall Street Journal’s Jeremy Singer-Vine reports that researchers at the Tokyo University of Science have used stem cells to grow a replacement tooth for a mouse. A report in the Proceedings of the National Academy of Sciences reports that this is the first time that scientists have developed a fully functioning three-dimensional organ replacement using stem cells.
The scientists created a set of cells that contained genetic instructions to build a tooth, and then implanted it into the mouse’s tooth socket. The tooth grew in the same manner that a natural one would. After 11 weeks, it had a similar shape, hardness and response to pain or stress as a natural tooth, and worked equally well for chewing. The researchers suggested that using similar techniques in humans could restore function to patients with organ failure.
Dr. Max Gomez of WCBS TV reports on a clinic near Denver, Colorado that is using adult stem cells to treat osteo-arthritis of the knee, hip, ankle, and even back pain. Dr. Christopher Centeno and two of his patients discuss the process and their experience.
BBC News reports that researchers in Sao Paulo, Brazil have discovered that fallopian tubes are an abundant source of mesenchymal stem cells. Because fallopian tubes normally are discarded during surgeries such as hysterectomies, they may be good source for non-controversial donor cells for regenerative medicine. In addition, the researchers anticipate that the cells could be useful for understanding and treating fertility problems. The researchers’ findings were published in the Journal of Transitional Medicine.
Alan Mozes of BusinessWeek’s HealthDay reports on a milestone in stem cell research. Chinese scientists have grown healthy, fertile mice by using pluripotent stem cells (iPS) derived not from controversial embryonic stem cells, but instead from those of adult mice.
Birmingham Business Journal - Jimmy DeButts reports in article entitled “UAB to Bring Jobs, Research through Stem Cell Institute.” The University of Alabama at Birmingham is building on the success of its existing biotech research facilities to create a Stem Cell Institute.
Tom Blackwell of the National Post reports that Toronto-based researchers have found that usually discarded umbilical cords are a plentiful source of mesenchymal stem cells. A group of researchers at Princess Margaret Hospital and the University of Toronto in Ontario say they’ve discovered that umbilical cords are a “virtually inexhaustible” and non-controversial source of promising stem cells.
Paula Moyer reports for Dermatology Times that researchers believe adult stem cells may have a greater role in wound healing in the future. William J. Landis, Ph.D., at the Northeastern Ohio Universities Colleges of Medicine and Pharmacy says that he and his co-workers have been conducting tissue-engineering research with bovine models to learn if stem cells can heal wounds in bones, cartilage and tendons. "Dermatologists should know that investigators are exploring the possibility of promoting wound healing with stem cell treatments,” he said.
"Serious cutaneous and connective tissue pathologies should be treatable with stem cells. This is an area of medicine that has broad potential, and I would encourage dermatologists to be involved in the research investigating stem cell use for wound healing in as wide a spectrum of applications as possible," Dr. Landis said.
Dr. Landis reports that stem cells may be readily available from a variety of sources, including cord blood and bone
The University of Florida’s John Pastor reports that researchers at the university have programmed bone marrow stem cells to repair damaged retinas in mice. This suggests that there is potential to treat common causes of vision loss in humans, such as macular degeneration, which affects nearly 2 million people in the United States, and some forms of blindness related to diabetes.
Researchers removed blood stem cells from the bone marrow of mice, modified the cells in cultures, and injected them back into the animals’ circulatory systems. From there, the stem cells were able to hone in on the eye injury and become retinal cells. At 28 days after receiving the modified stem cells, mice that had previously demonstrated no retinal function were no different than normal mice in electrical measures of their response to light.
The University of Florida’s College of Medicine reports that the success in repairing a damaged layer of retinal cells in mice implies that blood stem cells take
Medical News Today reports that the Center for Stem Cell & Regenerative Medicine has received $5 million in funding from Ohio’s Third Frontier Commission under the Research Commercialization Program. The Ohio Third Frontier is a bipartisan organization whose aim is to promote the state’s technological strengths and help with commercialization of technologies.
The funding will help support new and innovative stem cell technologies including two commercial, four emerging and three pilot projects. This funding will be matched by each of the projects to create a $10 million grant benefiting stem cell and regenerative medicine in Ohio. The Center for Stem Cell & Regenerative Medicine (CSCRM) is comprised of Case Western Reserve University (CWRU), Cleveland Clinic (CC), University Hospitals (UH), and Athersys, Inc., a clinical stage biopharmaceutical company.
"This funding provides CSCRM the support it needs to continue to aggressively move new technologies from academic
Promising research which may potentially improve a person’s recovery after suffering a heart attack.
ScienceDaily reports that biomedical engineering students at Johns Hopkins University have demonstrated a way to embed a patient's own adult stem cells in the surgical thread that doctors use to repair serious orthopedic injuries such as ruptured tendons. The goal, the students said, is to enhance healing and reduce the likelihood of re-injury without changing the surgical procedure itself.
At the site of the injury, the stem cells are expected to reduce inflammation and release growth factor proteins that speed up healing, enhancing the prospects for a full recovery and reducing the likelihood of re-injury.
In collaboration with orthopedic physicians, the team's preliminary experiments in an animal model have yielded promising results. Provided the trials continue to be successful, it is estimated that possible human trials could take place within about five years.
“We believe the stem cells will significantly speed up and improve the healing process,” said Ma
Laura Ungar of the Louisville Courier-Journal reports on one of the world’s first recipients of an infusion of cardiac stem cells as a part of a Phase 1 clinical trial being conducted by a team of University of Louisville physicians at Jewish Hospital.
Study aims to learn whether treating newly diagnosed Type 1 diabetics with adult stem cells can either slow or stop the progression of their disease, thereby reducing or even eliminating insulin dependence.
Researchers from the City of Hope National Medical Center have reported on a study that suggests that there continues to be improvement in the results of stem cell treatments for patients with secondary leukemia and myelodysplasia.
The Reporter’s Kathy Whitney reports that Vanderbilt Heart and Vascular Institute recently enrolled its first patient in a Phase II clinical trial using stem cell treatments aimed to reverse damage to the patient's cardiac muscle caused by heart disease.
CEO praises legislative progress to date and encouraging continued momentum for existing bills through the second half of the year.
Forbes.com reports that American physicians have performed the first procedure in which a patient received injections of his own heart stem cells to repair cardiac muscle damaged by heart attack.
Eastern Virginia Medical School (EVMS) is conducting this double blind study on the effectiveness of a new therapy using adult stem cells to treat type 1 diabetes.
There are many treatments and therapies for stroke victims. Today, the most widely used are various medications, often combined with physical and/or speech therapy. In addition to medication and physical therapy, there is promising research on the benefits of stem cell treatments for stroke victims.
Dayton Ohio Daily News reports that the state’s house unanimously voted in favor of the Cord Blood Education Bill. Under this bill, pregnant women in the state of Ohio would be told about the benefits of storing their newborn’s umbilical cord blood.
The Houston Chronicle reports that doctors from the University of Texas Medical School have launched the nation's first experimental trial to treat stroke patients with their own stem cells.
This new treatment is directed at patients who were not able to receive a tissue plasminogen activator or who did not respond to the treatment, which is reported as the only treatment available now for stroke victims.
Neurologist and Professor Sean Savitz reported that the trial's first patient was treated on March 25, 2009 and is doing well. "We're just at the beginning, but this could be an exciting new area of therapeutic intervention for stroke," said the doctor, adding, "It could be the next frontier."
Over the past four years, the Reina Sofía hospital in Córdoba, Spain has been conducting clinical trials using stem cells to treat patients who have suffered one or more heart attacks. One trial in particular, completed in 2007, concluded that one type of stem cell therapy showed great promise. The test consisted of 30 patients who had suffered severe myocardial infarction, or an obstruction of a main coronary artery.
One third of the patients received standard treatment; the second group was treated with a medication called G-CSF, which makes cells move from the marrow to the blood, thereby reaching the heart. The third group received stem cells from their bone marrow, which were implanted directly into the coronary artery via catheter.
Science Daily reports that researchers at the University at Buffalo have demonstrated that injecting adult bone marrow stem cells into skeletal muscle can repair cardiac tissue and reverse heart failure.
The study, performed on an animal, showed that this non-invasive procedure increased the number of heart cells two-fold and reduced cardiac tissue injury by 60 percent. It also showed an improved function of the left ventricle, the heart’s primary pumping chamber, by 40%, and reduced fibrosis, the hardening of the heart lining that impairs its ability to contract, by 50%.
The novel method of delivering mesenchymal stem cells (MSCs) via an intramuscular route is preferable over clinical trials which have focused more often on invasive procedures such as introducing stem cells directly into the heart. These methods carry more risks and can result in harmful scar tissue, arrhythmia, calcification or small vessel blockages.
"For these reasons, and because patients with heart failure
Phase I trial investigating the potential use of stem cells to help reduce or eliminate kidney transplant patients’ reliance on anti-rejection medications
The cardio-thoracic department of Chennai-based Sri Ramachandra University and Dr. Naresh Trehan's center in New Delhi have joined forces to conduct stem cell research for heart attack victims undergoing a by-pass surgery. The stem cell therapy will involve the patients receiving stem cell shots during the operation. This stem cell research will start after the department of biotechnology gives its nod for the pilot project. Scientists hope this stem cell treatment will enrich the heart cells and repair damages caused due to cardiac arrest. Dr. Amit N Patel, Director of Cardiac Stem Cell Therapies at the McGowan Institute of Regenerative Medicine, says injection of stem cells improve the function of muscles and blood vessels allowing patients to lead a near-normal life.
Doctors say new stem cell research could fight a form of heart disease. Doctors in the Netherlands injected bone marrow and stem cells into the heart of 50 patients, all suffering from a chronic heart condition. Some got a placebo instead of the stem cells. Three months after the procedure, those who got the real stem cell treatment had improvements in blood flow and heart function, exercise capacity and overall quality of life.
Cryo-Cell International, Inc. announced results of a new study showing that adding menstrual blood stem cells (MenSCs) to stem cells from umbilical cord blood expands the number of progenitor cells (cells that grow into mature blood cells). This expansion technique could broaden the therapeutic use of the cells and provide a more readily available supply of stem cells for transplantation.
Each morning 11-year old Holly Arvidson wakes, she hopes it will be the day she will be given sight.
Holly and her family have returned from China where the 11-year-old from Denman underwent the first round of a controversial stem cell treatment which will hopefully result in her being able to see. Holly, who was born blind, is believed to be the 20th child to travel to china from Australia for stem cell treatment which has not been approved in the country. The treatment, which involves a number of stem cell injections over a four-week period, is achieving results and has an 80 per cent success rate, Mrs. Arvidson said. The Arvidsons hope that over the next six months Holly's vision will progressively start to improve and she will gain some light perception. "The second treatment should bring sight and a third even better sight. We plan to return to China next year," Mrs. Arvidson said.
Don Otte is betting on stem cell therapy to completely annihilate the cancer he has been battling for the past 16 years. Otte, the county commissioner for Stearns County Minnesota, was diagnosed in 1992 with non-Hodgkin’s lymphoma. At the time doctors told him he would be dead in five years. Through self-education and actively seeking out new and sometimes unorthodox treatment methods, Otte has managed to stick around much longer than expected. Over the past decade Otte has undergone numerous radiation and chemotherapy treatments as well as some unconventional treatments like shark cartilage pills and having the fillings removed from his teeth, believing that the mercury was suppressing his immune system. During this time the cancer went into remission. But it soon showed up elsewhere in his body, including fast-growing cells in his knee and his chest cavity. During a four-year period, Otte tried three different experimental drugs, including one that caused severe muscle cramping. When
New research at the University of Minnesota shows natural killer cells taken from human embryonic stem cells are more effective at killing tumors than cells taken from other sources. A research team led by Dan Kaufman, M.D., Ph.D. demonstrated natural killer cells from human embryonic stem cells are better at killing human leukemia in mice, preventing the cancer from metastasizing in any of the animal’s organs. The study has also shown stem cell-derived tumor-killing cells are highly effective in killing breast cancer, prostate cancer, testicular cancer and brain tumor cells.
For an expectant mother, there are a million details to worry about and a lot of important decisions to be made. One of those decisions to be made is whether to bank your baby's umbilical cord blood. Cord blood is valuable because it's full of stem cells scientists and doctors can use in research and regenerative medicine. Right now cord blood stem cells are being used to treat more than 70 life-threatening diseases including a wide range of cancers, blood disorders, immune system deficiencies and genetic diseases.
NBC Los Angeles features a new study in which recently diagnosed diabetic children are being treated with stem cells from umbilical cord blood.
A treatment available in China may help 7-year-old Riley Cox see, hear and play for the first time in her life. Riley has optic nerve neuropathy, hydrocephalus -- water on the brain -- cerebral palsy and is deaf and blind. She was born four months prematurely and spent six months in the neonatal intensive care unit at Memorial Hospital in South Bend. Optic nerve neuropathy is a disorder causing a lack of oxygen to the optical nerve. Riley had undergone several operations as an infant to save her eyesight but none were successful. Now Riley’s mom is banking on an experimental treatment to give Riley some vision and give her a reprieve from her everyday battle. She is reaching out to family, friends and neighbors to help her raise the $30,000 it takes get Riley to Hang-zhou, China and receive the stem cell treatment. Cox hopes the stem cell therapy will restore some of her vision and, she hopes, help with her other disabilities. In China, Riley would receive seven treatments, with the f
Research Study Will Explore Therapeutic Cellular Platform Utilizing Cord Blood
and Menstrual Blood Derived Stem Cells in the Formation of Emergent Vascular